CRO Services: Full-Service Contract Research & Full-Lifecycle Clinical Trial Management

Alpha Clinical Development provides full-service contract research and full-lifecycle clinical trial management, with a specialist focus in oncology, immunology and rare disease — supporting sponsors from proof-of-concept through late-stage programmes. This is not generalist, high-volume CRO delivery; it is physician-informed clinical operations built for protocols where site scarcity, patient eligibility and safety complexity are the norm, not the exception.

Led by Dr. Stephen B. Shrewsbury, Scientific Advisor — 31+ years in global pharma

Capabilities

Capabilities at a Glance

STUDY START-UP & ACTIVATION

CLINICAL MONITORING & BIOMETRICS

SITE MANAGEMENT & PATIENT-CENTRIC SOLUTIONS

PROJECT MANAGEMENT

In practice

What This Means in Practice

Study start-up begins with rigorous site feasibility and selection, not a generic site list — every site is evaluated on real capability to deliver the specific protocol, not just historical enrolment volume. Site contracts and budget negotiation, and patient access planning, run in parallel so first-patient-in is never delayed by a paperwork bottleneck. Recruitment and retention strategy is built around the realities of oncology, immunology and rare disease populations, where the eligible patient pool is often measured in dozens, not thousands.

Clinical monitoring blends targeted source data verification with full biometrics support — data management, biostatistics and statistical programming delivered against CDISC/SDTM/ADaM standards, plus physician-led clinical adjudication where endpoint or safety-event review calls for genuine clinical judgement rather than a coding convention. Site management stays patient-centric throughout: specialised physician support, active medical monitoring, and patient advocacy and engagement built into the operating model rather than bolted on.

Project management runs on CTMS and eTMF infrastructure with risk-based quality management as the default posture, not an occasional audit exercise, with transparent reporting so sponsors always have one accurate view of study status.

Why Alpha

Why Sponsors Work With Alpha

Alpha keeps a single senior clinical lead accountable from study start-up through database lock and CSR delivery — the same physician-led oversight model that runs across every Alpha business unit. Deep therapeutic focus in oncology, immunology and rare disease is matched by genuinely global reach: offices across the USA, UK, Canada and UAE support ICH-GCP-compliant trial delivery internationally, without the additional management layers a much larger CRO would add. And because CRO Services, Pharmacovigilance, Consulting and Sourcing Solutions all sit inside one organisation, safety oversight, regulatory strategy and resourcing decisions are never a separate, disconnected conversation from clinical operations.

Trials Supported

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FDA-Approved Drugs Supported, incl. Rare Disease

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EMA Marketing Authorisations Supported

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Insights

From Alpha Insights

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